Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Now in its second edition, this atlas serves as an easy-to-use diagnostic guide for the analysis of the human karyotype. Split in four parts, it starts with a comprehensive introduction covering the molecular cytogenetic basics, the role of ethic committees and international quality control in the field of diagnostics. The main parts II and III, demonstrate the spectrum of the different types of chromosome abnormalities by a combination of karyogram and ideogram, it compares the expressiveness of different banding techniques, and it gives the karyotype formula and describes morphological peculiarities of each presented case. The final part, provides a detailed description of variants of non-coding DNA and focuses on potential problems in detecting aberrations and mentions necessary additional investigations and peculiarities, which have to be taken into account when counseling carriers of a chromosome aberration or their relatives. Given its comprehensive scope and practical approach, this atlas is an indispensable resource for researchers, clinicians and practitioners working in the field of cytogenetics and clinical genetics.

Human chromosomes.

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Chromatin. --- Chromosomes --- Nucleoproteins

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book describes current knowledge about the mechanisms by which cells segregate their already duplicated chromosomes in preparation for cell division. Experts in the field treat several important aspects of this subject: (1) the history of research on mitotic mechanisms, to serve as a background; (2) assembly of the mitotic spindle; (3) Kinetochore assembly and function; (4) the mechanisms of chromosome congression to the metaphase plate; (5) the spindle assembly checkpoint; (6) mechanisms to avoid and correct erroneous chromosome attachments to the spindle; (7) a molecular perspective on spindle assembly in land plants; (8) chromosome segregation in anaphase A; (9) spindle elongation in anaphase B; and (10) the consequences of errors in chromosome segregation. Each chapter provides the reader with a comprehensive and accurate picture of current research in a form that is both readable and authoritative. The volume is suitable for scholars in this and related fields and for teaching at an advanced level.

Cell cycle. --- Chromosomes.

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Human genome. --- Genomes --- Human chromosomes

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

"Chromatin regulation and dynamics integrates knowledge on the dynamic regulation of primary chromatin fiber with the 3D nuclear architecture, and then connects related processes to circadian regulation of cellular metabolic states, representing a paradigm of adaptation to environmental changes. The book also covers the many ways chromatin dynamics can synergize to fundamentally contribute to the development of complex diseases. Chromatin dynamics, which is strategically positioned at the gene-environment interface, is at the core of disease development. As such, Chromatin regulation and dynamics, as part of the Translational epigenetics series, facilitates the flow of information between research areas such as chromatin regulation, developmental biology, as well as ageing and complex diseases by focusing on recent findings of the fast-moving field of chromatin regulation."--

Chromatin --- Research --- Methodology. --- Chromosomes --- Nucleoproteins